Strong Dependence of Infection Profiles on Grouping Dynamics during Epidemiological Spreading

نویسندگان

  • Zhenyuan Zhao
  • Guannan Zhao
  • Chen Xu
  • Pak Ming Hui
  • Neil F. Johnson
چکیده

The spreading of an epidemic depends on the connectivity of the underlying host population. Because of the inherent difficulties in addressing such a problem, research to date on epidemics in networks has focused either on static networks, or networks with relatively few rewirings per timestep. Here we employ a simple, yet highly non-trivial, model of dynamical grouping to investigate the extent to which the underlying dynamics of tightly-knit communities can affect the resulting infection profile. Individual realizations of the spreading tend to be dominated by large peaks corresponding to infection resurgence, and a generally slow decay of the outbreak. In addition to our simulation results, we provide an analytical analysis of the run-averaged behaviour in the regime of fast grouping dynamics. We show that the true run-averaged infection profile can be closely mimicked by employing a suitably weighted static network, thereby dramatically simplifying the level of difficulty.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Staphylococcus epidermidis biotype 4: epidemiological conclusions from five different typing methods.

There is presently no accepted method for marking individual strains of Staphylococcus epidermidis. Consequently, five parameters for distinguishing such strains were examined and compared for their epidemiological efficacy: biotyping, serotyping, proteinase grouping, aminopeptidase profiles and antibiograms. Both biotyping and proteinase grouping were of limited use in identifying a particular...

متن کامل

Atypical viral dynamics from transport through popular places.

The flux of visitors through popular places undoubtedly influences viral spreading-from H1N1 and Zika viruses spreading through physical spaces such as airports, to rumors and ideas spreading through online spaces such as chat rooms and social media. However, there is a lack of understanding of the types of viral dynamics that can result. Here we present a minimal dynamical model that focuses o...

متن کامل

Stochastic Simulation of HIV Population Dynamics through Complex Network Modeling

Despite the availability of a large number of mathematical models describing the spreading of HIV, a good understanding of the spreading dynamics through numerical analyses is still a major challenge. The true incidence of the HIV/AIDS-epidemic is quite uncertain since many people may be unaware of their infection; moreover HIV has a very long asymptotic incubation period which makes study of t...

متن کامل

A review on West African Ebola epidemic dynamics models

Background and aims: The world is threatened by disease outbreak that reaches a public health emergency of international concern, studies to inform public and agencies for effective containment strategy are necessary. Several studies provided vital information of the dynamics and control of Ebola epidemic outbreak in West Africa. Methodologies and techniques in those researches...

متن کامل

On the risk of severe dengue during secondary infection: a systematic review coupled with mathematical modeling.

BACKGROUND & OBJECTIVES The present study aimed to systematically quantify the well known risk of severe dengue during secondary infection in literature and to understand how epidemiological mechanisms of enhancement during the secondary infection influence the empirically estimated risk of severe dengue by means of mathematical modeling. METHODS Two conditional risks of severe dengue, i.e. s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009